The pathology of the diseases of the cardiovascular System
The pathology of the diseases of the cardiovascular System
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The pathology of the diseases of the cardiovascular system: A silent epidemic The almost is due any second cause of death in the industrialized countries, on the diseases of the cardiovascular system, makes it clear that These diseases have become a true people's disease. This term refers to a wide variety of Suffering, from the atherosclerosis lies on the coronary heart disease to strokes and heart failure. But what exactly is at a pathological level incorrectly when the circulatory system fails? The Central role is played often in the atherosclerosis — the hardening and hardening of the vessel walls. In fat, cholesterol and calcium deposits accumulate Inside of the arteries. These so-called Placken to narrow the vessel lumen and impede blood flow. A Plaque is unstable, it can tear. Then a blood clot (Thrombus), which can occlude the vessel fully formed quickly. This results in a heart artery to the lock, is created to die of a heart attack is a life-threatening emergency situation, in the heart muscle tissue. In addition to the mechanical narrowing of the Endothelial dysfunction plays a crucial role. The endothelium of the vessels in the inner lining of the blood, normally regulates the vascular tone, blood coagulation, and inflammatory responses. In pathological States, it loses these functions, which leads to increased inflammation and vasoconstriction. The heart itself can be pathological to be changed. In the case of hypertensive heart disease of the left heart ventricle must fight against an increased pressure (e.g., hypertension). As a result of its wall (Left ventricular hypertrophy) thickens. First of all, this is an adaptive response, in the long term, however, it makes the relaxation and filling of the heart and can lead to heart failure — a condition in which the heart can no longer pump enough blood to the body. Risk factors accelerate these pathological processes. Among them are: High Blood Pressure (Hypertension), Diabetes mellitus, Smoking Overweight and obesity, Lack of movement, an unhealthy diet high in salt and fat content, Genetic Disposition. The pathological changes in the cardiovascular system often develop over years or decades, long before symptoms occur. This latent Phase, makes the disease so dangerous: Many people are unaware of the risks and take preventive measures. The good news is that Many of these diseases are präventierbar. A healthy lifestyle — regular physical activity, a balanced diet, giving up Smoking, and the control of blood pressure and blood sugar can slow down the development of atherosclerosis and other pathologic changes significantly, or even prevent them. Conclusion: The pathology of the cardiovascular system is complex, however, their main causes are not known. By informing us about the risk factors and our life style, we can protect our heart and our blood vessels — and therefore, the silent epidemic together to combat it.
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Risk factors for cardiovascular diseases Cardiovascular disease causes are one of the leading death in the world. Its Occurrence is influenced by a variety of risk factors can be divided into modifiable and non-modifiable categories. Non-modifiable risk factors Among the non-modifiable risk factors: Age: With age, the risk for heart increases cardiovascular disease significantly. In men, the risk is over the age of 45. Age increased in women from the age of 55. Age or after Menopause. Gender: men are generally exposed to greater risk than women in the premenopausal age. After Menopause, the risk approach, the probabilities of both sexes. Genetic Disposition: A family history of early‑onset cardiovascular disease (it is in men before the age of 55. Age, and in women before the age of 65. Years of age), increases the individual's risk. Modifiable Risk Factors The modifiable risk factors through changes in behaviour and medical interventions affect: High blood pressure (hypertension): A permanently elevated blood pressure (≥140/90 mmHg) charged to the vessels of the heart and blood, and promotes atherosclerosis. Elevated cholesterol levels: in Particular, increased levels of LDL cholesterol (bad cholesterol) and low HDL‑cholesterol (good cholesterol) favor Placken the formation of atherosclerosis. Diabetes mellitus: Diabetes, the risk for cardiovascular disease is significantly increased, since the blood vessels are damaged and the Lipid metabolism are disturbed. Overweight and obesity: A Body Mass Index (BMI) ≥30 kg/m 2 as well as a waist circumference >increase of 102 cm in men and >88 cm in women, the risk of. Lack of exercise (Hypodynamie): insufficient physical activity promotes Obesity, hypertension, and metabolic disorders. Smoking: The Smoking of tobacco products causes damage to the vascular inner layer, increases the heart rate and the blood pressure and promotes thrombus formation. Excessive consumption of alcohol: Chronic excessive consumption of alcohol can lead to high blood pressure, heart muscle damage (alcoholic cardiomyopathy), and arrhythmias. Stress: Chronic Stress can smoke to increased blood pressure, unhealthy living habits (e.g., unhealthy diet) and other risk factors contribute. Synergistic Effects Especially dangerous is the combination of several risk factors. The risk of simultaneous multiplies the Presence of hypertension, hypercholesterolemia and Diabetes. This combination is referred to as the metabolic syndrome and is an important starting point for prevention measures. Conclusion The identification and modification of risk factors plays a Central role in the prevention of cardiovascular diseases. While non-modifiable factors such as age and genetics form the basis for, provide modifiable factors, the width of the starting points for individual and social prevention strategies. Regular medical check-UPS, healthy lifestyle, and targeted drug therapy can reduce the individual risk significantly.