Cardiovascular and oncological diseases
Cardiovascular and oncological diseases
Nililinis ang mga ugat na kailangang alagaan mula sa deposito at pinananatili ang kinakailangang lakas ng tibok ng puso!
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Cardiovascular diseases for Oncology patients: interactions and clinical challenges The treatment of oncological diseases has made in the last few decades, significant progress, which has led to an increased survival rate of cancer patients. At the same time, an important Problem is in the foreground: the incidence of cardiovascular diseases (HKK) in this group of patients is increasing. This development is due to both the increase in life expectancy after cancer treatment, as well as to the cardiotoxic effects of many therapies. Cardiac toxicity of oncological therapy procedures Many of the standard therapies for cancer, especially chemotherapy and radiation therapy, can exert adverse effects on the heart and the vascular system. Among the most commonly responsible substances Anthracyclines (e.g., Doxorubicin), tyrosine kinase inhibitors and immune therapies. Anthracyclines can lead to a Doxorubicin-induced cardiomyopathy, which is characterized by a reduction in the left ventricular ejection performance. Radiation therapy in the Thoracic region, in turn, increases the risk for pericarditis, coronary artery disease, and Valvular. Risk factors and common Pathomechanisms A number of factors increases the risk for the development of HKK in Oncology patients: pre-existing cardiovascular disease prior to the start of cancer treatment; higher age; metabolic disorders (Diabetes mellitus, hyperlipidemia); Style factors (Smoking life, lack of physical activity). In addition, recent studies show that oncogenic signaling pathways and inflammatory processes in tumor development as well as in the development of atherosclerosis play a role. This common biological mechanisms may increase the risk for cardiovascular complications in cancer patients. Diagnostics and Monitoring Early detection of cardiac damage is crucial for the prevention of severe complications. Among the most important diagnostic procedures: Echocardiography for evaluation of cardiac function; The determination of biomarkers, such as Troponin and N‑terminal pro-B-type Natriuretic peptide (NT-proBNP); cardiac resonance imaging (MRI) magnet for a detailed assessment of myocardial changes. Regular Monitoring during and after the completion of the Oncology therapy, allows for the timely Intervention can prevent the progression of cardiac dysfunction. Therapeutic strategies and multidisciplinary care The treatment of cardiovascular complications in cancer patients requires an individualized approach. In many cases, cardio‑used-protective drugs (e.g. ACE-inhibitors, beta-blockers), in order to stabilize the function of the heart. A special focus is on the close cooperation between cardiologists and oncologists — a concept that is referred to as cardio-Oncology. This multi-disciplinary care allows you to: Consideration of the Benefit‑risk ratio in the selection of therapies; early identification of patients with high cardiovascular risk; Development of individual prevention and treatment strategies. Summary and Outlook Cardiovascular disease in patients with oncological diseases is a growing challenge. The implementation of preventive measures, regular Monitoring, and multidisciplinary care can improve quality of life and improve survival duration of these patients significantly. Future research should focus on the development of new cardio‑ protective strategies, as well as on the optimization of Screening and monitoring protocols.
Cardiovascular and oncological diseases. Diuretiko (Diuretika) ay nagpapataas ng pag-ihi ng katawan, na nagreresulta sa pagbaba ng presyon ng dugo. Simpleng paliwanag: Ang tuloy-tuloy na pag-ihi ng katawan ay nagdudulot ng pagbaba ng dami ng plasma sa dugo at sa gayon ay mas kaunting likido sa mga ugat — bumababa ang presyon sa mga pader ng ugat.
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Constant high levels of stress can disturb the blood flow and blood pressure and can damage vessels, and you may experience dizziness, extreme fatigue, or body aches with no wish to get out of bed. This stress-induced fatigue can make your blood pressure high and needs to be monitored. Ginagamit ito bilang biologically active na pampadagdag sa pagkain — dagdag na pinagmumulan ng mga bitamina — B2, B6, C, mga organikong asido — mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6.
Catheter ablation in the case of cardiovascular disease: techniques, indications and results The catheter ablation represents an important therapeutic Option in a number of cardiovascular diseases, especially in the case of arrhythmias. This minimally invasive procedure allows for the targeted destruction (Ablation) of heart tissue for the formation and maintenance of pathological cardiac rhythm disturbances and is responsible. Process technology During the catheter ablation of a thin, flexible catheter through a vein or artery (typically the femoral vein) into the heart. Using electrophysiological investigations will first identify the exact Origin, locations of the arrhythmogenic activity. It is then passed through the catheter energy (mostly radio-frequency energy or cooling energy by means of cryotherapy) to the affected area, damage to the arrhythmogenic tissue specifically, or to destroy it. This under the abnormal breaks runs electric circuit and can restore the normal heart rhythm. Indications The catheter ablation at different Arrhythmia types, including: Atrial fibrillation (atrial fibrillation): One of the most common indications, especially when the drugs don't work enough or intolerable side effects. Atrial flutter (atrial flutter): Often with a very high degree of Success treatable, there is typically a clear defined in the Reentry circuit. Paroxysmal supraventricular tachycardia (PSVT): Including AV‑Nodal‑Reentry tachycardia (AVNRT) and orthodrome AV Reentry tachycardia (e.g. Wolff‑Parkinson‑White syndrome). Ventricular tachycardia In patients with structural heart disease (e.g. myocardial infarction) can the Ablation, the risk of cut life-threatening arrhythmias and the need for Implantable cardioverter‑defibrillators (ICD) reduce. Results and risks The success of catheter ablation varies depending on the arrhythmia type. In the case of simple arrhythmias such as atrial flutter or PSVT, the success rates are over 90%. In the case of more complex forms, such as atrial fibrillation repeated interventions are often necessary, and the initial success rates are about 60-80%. Despite the minimally invasive nature of the procedure, there are risks, including: Vascular complications at the puncture site Cardiac perforation or Tamponade Stroke (especially in atrial fibrillation ablation) AV‑Blockade, which may require a permanent pacemaker Pulmonary vein stenosis (rare, especially in the case of atrial fibrillation ablation) Conclusion Catheter ablation has been established as an effective treatment method for many arrhythmias. It provides patients with medications fail or incompatible, a realistic Alternative with high chances of success. The continuous development of the techniques and navigation systems, as well as the improvement of the understanding of the arrhythmogenic mechanisms are expected to increase the efficiency and safety of the procedure. Careful patient selection and a multidisciplinary approach are essential in order to achieve the best possible results.